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A medicine currently being tested as a chemoprevention agent for multiple types of cancer has more than one trick in its bag when it comes to preventing stomach cancer, Vanderbilt researchers have discovered.

VUMC has received significant grants to study pulmonary fibrosis, a progressive and irreversible disease characterized by shortness of breath and a dry cough.

Jason McGurn and colleagues have uncovered new insights into the complex and highly coordinated endocytic trafficking mechanism, which is an essential part of many cellular processes including sodium resorption by the kidney and regulation of blood plasma sodium levels. Read More

A $3.4 million grant from the National Institute of Mental Health will fund Vanderbilt research on treatment resistance in patients with major depressive disorder and schizophrenia.

Commonly thought to be harmless, enlargement of fluid-filled in the brain have been linked to cognitive problems in older adults.

Young women with separation anxiety tend to over-rely on external cues to define themselves, which can make them vulnerable to internalizing unhealthy body ideals. Read More

Vanderbilt researchers are on a quest to develop early biomarkers of treatment outcomes for patients with temporal lobe epilepsy based on their individual brain networks.

Lauren Woodard and Matthew Wilson have discovered a way to reprogram adult human kidney cells into cells similar to those that form during embryonic development, which could lead to new kidney disease treatments.

Though neurological activity is generally associated with the brain's gray matter, Muwei Li and colleagues have now measured it in white matter as well.

New research into the enzyme topoisomerase II sheds light on how it helps DNA replicate properly. Read More

Stimulating the vagus nerve triggers certain epigenetic changes involving learning and memory. Read More

Normal brain aging patterns in patients with a psychotic disorder occur at an accelerated rate, impacting the patient’s cognitive functioning and suggesting treatment intervention in the early psychosis period may improve long-term outcomes.

Heidi Hamm and colleagues have reported the first animal model of a "shut-off valve" for neurotransmitter and hormone release through SNARE complex-mediated membrane fusion.

David Cortez and colleagues have discovered a new DNA repair mechanism.

A team of Vanderbilt researchers mapped out the genomic landscape of a metastatic malignant proliferating tricholemmal tumor and identified a targeted treatment for this very rare cancer.

Researchers at Vanderbilt University Medical Center and colleagues have identified a gene that increases the risk for a severe and potentially life-threatening reaction to the commonly prescribed antibiotic vancomycin.

Loss of the protein STK17A may contribute to metastasis of colorectal cancer.

People with low levels of endocannabinoids, which stimulate the same brain receptors turned on by the active ingredient in marijuana, experience greater pain relief from opioids than those with high levels.

A team of Vanderbilt University chemists started decoding the total human molecular picture by examining 456 variations of one class of molecule, lipids. Read More

A big-data analysis of patient records at Vanderbilt University has found a link specifically between Celebrex and heart valve calcification. Read More