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VUMC has joined an international effort to streamline and accelerate development of vaccines and other treatments against a growing worldwide surge of deadly and debilitating viral infections.

Microbial species in the mouth could be playing a role in colorectal cancer development, according to new research from epidemiologists at VUMC.

A new study published in Neurology reports the drug trofinetide has proven safe and effective in treating core symptoms of Rett syndrome in female children and adolescents.

A study from Vanderbilt’s Center for Biomedical Ethics and Society is bringing renewed focus on the concept of comprehension of informed consent for research purposes.

Vanderbilt University researchers have discovered how a protein pump distinguishes between chemicals that it will expel from a cell and inhibitors that block its action. The new findings could guide the development of more efficient inhibitors to prevent cancer cell resistance to chemotherapy.

The flu mutates so quickly that we need a new vaccine every year, but Vanderbilt scientists have found a vulnerable part of the virus that doesn't mutate as much.

Seasonal light exposure during pregnancy had effects on serotonin and depression that persisted into adulthood in mice. Read More

Basement membranes are important structural and functional components of tissues. New research provides insight into how they repair themselves.

New findings may speed progress toward programming cells to rebuild damaged hearts more quickly.

Benign lesions caused by a common fungus can mimic those caused by cancer in the lungs. A Vanderbilt research team is on the hunt for a non-invasive way for doctors to tell the two diseases apart. Read More

Asian countries are in the early stages of a tobacco smoking epidemic with habits mirroring those of the United States from past decades, setting the stage for a spike in future deaths from smoking-related diseases.

Using a unique computational framework they developed, a team of scientist cyber-sleuths in the Vanderbilt University Department of Molecular Physiology and Biophysics and the Vanderbilt Genetics Institute has identified 104 high-risk genes for schizophrenia.

Eric Skaar and colleagues have figured out how a common bug responsible for ventilator-associated pneumonia responds when starved of zinc, a metal it needs to survive, which may lead to new therapeutic targets for the dangerous infection.

A report by researchers at Vanderbilt University Medical Center has shattered conventional wisdom about how cells, including cancer cells, shed DNA into the bloodstream.

Jonathan Schoenecker, Stephanie Moore-Lotridge and colleagues have found a new target for treating a condition that causes bone to form in soft tissue, reducing mobility.

Vsevolod Gurevich and colleagues have discovered new insights into arrestin proteins, which turn off a cell's environmental message "inbox."

Austin Kirschner and colleagues are learning more about how the cancer drug enzalutamide combines with radiation therapy to treat difficult prostate tumors.

A commonly used muscle relaxant can cause severely low blood pressure in patients already taking a CYP1A2 inhibitor, such as ciprofloxacin, find Cecilia Chung and colleagues.

Jonathan Soslow and colleagues have found more clues to why people with Duchenne muscular dystrophy are at risk for a certain kind of heart problem.

Stephen Fesik and colleagues have uncovered more details about how a crucial component of RAS proteins, which trigger about a third of all tumors, work. This finding will help advance the discovery of new cancer therapies.