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Changing the gut microbiome to beat illness really does hold great potential, but first scientists must answer what constitutes a healthy gut microbiome and in whom. Read More

Researchers at Vanderbilt University Medical Center have identified a biomarker for insulin-producing beta cells. Their finding could lead to improved ways to study and treat diabetes.

New research by Jonathan Lehman and Pierre Massion have identfied a bioimarker that suggests poor prognosis for small-cell lung cancer, as well as potential target for new therapies.

Results of the study suggest the prospect of an array of individual and societal benefits to personalized medicine, as well as risks for physical, dignitary, group, economic, psychological and legal harms, many of which may have been over-emphasized or overlooked in the literature.

Tonia Rex and David Calkins were recently awarded National Eye Institute grants totaling $6.8 million over five years to develop new treatments for optic neuropathies and glaucoma, the leading cause of irreversible blindness.

A recent study led by Xiao-Ou Shu and colleagues found that green tea drinking was associated with increased risk of type 2 diabetes in Chinese adults, possibly due to the use of pesticides on tea plants--though the researchers call for further study of the exact mechanism.

Qi Liu, PhD, Ken Lau, PhD, and colleagues have developed a new tool, sc-UniFrac, to quantify diverse cell types in single-cell studies.

People with diabetes may be prone to more skin infections due to an overabundance of a compound that controls inflammation in the body.

In the first large-scale analysis of cardiovascular complications linked to immune checkpoint inhibitors, Vanderbilt researchers have identified several of the conditions that arise and have determined that they usually appear early in treatment.

It can take up to 16 years for a smoker's body to return to the same state of health as a non-smoker, but significant benefits do begin to appear right away, according to new research by Meredith Duncan.

Pulmonary hypertension may be treated by targeting a bone marrow cell that normally promotes the growth of new blood vessels, according to new research by David Merryman.

Patients hospitalized with a cardiovascular event are more likely to die within one year if they have low health literacy, according to new research by Lindsay Mayberry and Sunil Kripalani.

Susan Wente and Laura Glass have developed an experimental cell culture model system to investigate the link between stress granules and cell resistance to toxic stress, which could lead to new avenues for treating cancer treatment resistance.

Fiona Harrison and colleagues have found evidence that Vitamin C can help protect brains against seizures and cognitive decline in Alzheimer’s disease.

Rebecca Sappington and colleagues have found that increasing cGMP — part of a signaling pathway that was previously found to regulate intraocular pressure — protects retinal ganglion cells affected by glaucoma.

Lin Zhu and Rob Stafford have found that obesity interferes with cholesterol-improving CTEP inhibitors.

Jeffrey Rathmell and colleagues show that a drug that inhibits glutamine metabolism — currently in clinical trials as an anticancer agent — might also be useful as a treatment for inflammatory and autoimmune diseases.

Vanderbilt researchers led by Buddy Creech are searching for the key to lasting protection against influenza by examining naturally protecting cells found in bone marrow.

The grant will allow Charles Caskey to lead research into using ultrasound as an image-guided therapy for drug delivery.

The grant will allow Kennedy Center researchers to analyze data from VUMC's Synthetic Derivative and BioVU databanks to study biomarkers associated with Down Syndrome.