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Findings from a national study published Nov. 9 in the Journal of the American Medical Association (JAMA) “do not support” the use of hydroxychloroquine for the treatment of adult patients hospitalized with COVID-19, the report concludes.

Behavioral and systems neuropharmacologist Jerri Rook is recognized by the Alzheimer’s Drug Discovery Foundation with the Goodes Prize to continue her work in Alzheimer’s disease research. Read More

Jacek Hawiger’s anti-inflammatory peptide therapy, licensed by Amytrx and now in clinical trials, has the potential to safely and effectively treat a multitude of inflammatory and metabolic diseases. Read More

Biologists reveal that tissue perturbations by chemotherapy agents promote stem cell expansion and that fibroblast cells exhibit unexpected, immune-like behavior. Read More

Two prototype devices could refine thrombectomy through sensory augmentation.

All-remote collaboration results in free animal susceptibility tool to help prioritize research and closer examination of at-risk species. Read More

Nominations for the 2021 Vanderbilt Prize in Biomedical Science are now being accepted. The nomination deadline is Dec. 11.

Researchers at Vanderbilt University Medical Center have identified antibodies that, in animals, block infection by alphaviruses, which can cause chronic and debilitating joint pain and arthritis and are an increasing global health concern.

Vanderbilt University Medical Center has been awarded a one-year, $34-million grant by the National Center for Advancing Translational Sciences, part of the National Institutes of Health, to conduct a nationwide study of “convalescent plasma” as a treatment for COVID-19.

A small-molecule “scavenger” that reduces inflammation and formation of atherosclerotic plaque in blood vessels in mice potentially could lead to a new approach for treating atherosclerosis in humans, according to researchers at Vanderbilt University Medical Center.

Taking an interest in electronic message threads between surgical patients and their health care teams, a research group at Vanderbilt University Medical Center has tested how well certain commonly used machine learning algorithms can classify such exchanges according to their clinical decision-making complexity.

While 60 percent of people with metastatic melanoma, an aggressive type of skin cancer, have multiple treatment options available to them, roughly 40 percent either do not respond to treatment, or relapse.

An inflammatory factor in mucus could be a biomarker of treatment-resistant chronic sinusitis used to determine which patients are at risk for repeat sinus surgery.

Each week a woman consumes alcohol during the first five to 10 weeks of pregnancy is associated with an incremental 8% increase in risk of miscarriage, according to a study published this week by Vanderbilt University Medical Center researchers.

A computational technique that combines the effect of multiple genomic variants has the potential to identify high-risk individuals for cancer prevention.

Identifying the norovirus genotypes associated with more severe infections in children could guide strain selection for candidate norovirus vaccines.

Deborah Lannigan and colleagues identify a key regulator of the estrogen receptor and suggest that its downregulation by oral contraceptives may increase oxidative stress and DNA damage, a common cause of cancer.

A team of Vanderbilt University and Vanderbilt University Medical Center researchers has received a $3.1 million National Institutes of Health (NIH) grant to develop advanced, patient-specific cochlear implant stimulation models for customized implant programming.

The multicellular, 3-D structure of human pancreatic islets — the areas of the pancreas containing hormone-producing or endocrine cells — has presented challenges to researchers as they study and manipulate these cells’ function, but Vanderbilt University Medical Center researchers have now developed a pseudoislet system that allows for much easier study of islet function.

A protein linked to amyotrophic lateral sclerosis (ALS), a progressive neurological disease that causes muscle weakness, may be a key to treating fibrotic disease of the kidneys and other organs, researchers at Vanderbilt University Medical Center reported recently.